Ribosome Association and Stability of the Nascent Polypeptide-Associated Complex Is Dependent Upon Its Own Ubiquitination
نویسندگان
چکیده
منابع مشابه
Ribosome association and stability of the nascent polypeptide-associated complex is dependent upon its own ubiquitination.
In this work we addressed the role of ubiquitination in the function of the nascent polypeptide-associated complex (NAC), named EGD in the yeast Saccharomyces cerevisiae. To this end, we first identified the lysines residues required for ubiquitination of EGD/NAC. While simultaneous mutation of many lysines in the alpha-subunit of NAC (Egd2p) was required to abolish its ubiquitination, for the ...
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ژورنال
عنوان ژورنال: Genetics
سال: 2009
ISSN: 1943-2631
DOI: 10.1534/genetics.108.095422